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Microbiologic studies: Microbiology laboratory results of hospitals were evaluated retrospectively. Significant nosocomial pathogens, namely Pseudomonas spp., Escherichia coli, Klebsiella spp., Acinetobacter spp., Staphylococcus aureus obtained from at least one set of blood cultures of the inpatients were included. More than one set of the same isolates from the same patient were counted as one microorganism. All laboratories were using automatic blood culture systems (Bac-Tec® Becton-Dickinson, BacT-ALERT® BioMerieux) and performing antimicrobial resistance testing by Kirby Bauer disc diffusion method according to the recommendations of Clinical Laboratory Standart Institute (CLSI) [12]. Resistance patterns of ciprofloxacin, 3(rd) and 4(th) generation cephalosporins, (ceftazidime, ceftriaxone, cefepime), piperacillin-tazobactam, carbapenems (imipenem, meropenem), aminoglycosides (amikacin, gentamicin) against aforementioned pathogens were analysed. Bacterial idenfications were performed by conventional methods and automatic systems (API 20E® strips BioMerieux, BBL Crystal® Becton-Dickinson)..